Prediction is for three to four feet of snow in the Buffalo/Niagara area Thurs-Sat. As I write this, the forecast for Buffalo is 9-13 inches Thursday night, 5-9 inches daytime Friday, 6-10 inches Friday night, 2-4 inches daytime Saturday, and a few more inches (not specified yet since it's more than 48 hours out) Saturday night. It's the classic lake effect snow in the period when the air has gotten cold but the lakes haven't frozen yet so a lot of moisture gets picked up by the prevailing west-to-east winds and then dropped as snow by the cold air to the east. The effect generally doesn't extend all that many miles inland. In the meet area itself, west of Lake Ontario and not even 100km from Buffalo, hardly a flurry is predicted, when I last checked the Environment Canada
weather page for Hamilton.
You could go east of Lake Ontario, but there's significant lake effect snow predicted there too. You could go way way east by going all the way north through Vermont but there might be some lake effect snow from Lake Champlain (I didn't check, no doubt less than from the Great Lakes, if any). (EDIT: scratch that, forecast for Burlington, Vt, shows no snow.) You could go all the way around the west end of Lake Erie through Toledo-Detroit-Windsor, only a wee bit of snow predicted as long as you don't go too close to the south shore of Erie while getting there (I don't know if I-80/90 is too close).
Sadly, I've been intimidated into not attempting the trip myself, even though I'm registered and was really looking forward to it.